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・ Cheadle Hulme railway station
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CHB HEX N-terminal domain
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CHB HEX N-terminal domain : ウィキペディア英語版
CHB HEX N-terminal domain

In molecular biology, the CHB HEX N-terminal domain represents the N-terminal domain in chitobiases and beta-hexosaminidases. Chitobiases degrade chitin, which forms the exoskeleton in insects and crustaceans, and which is one of the most abundant polysaccharides on earth. Beta-hexosaminidases are composed of either a HexA/HexB heterodimer or a HexB homodimer, and can hydrolyse diverse substrates, including GM(2)-gangliosides; mutations in this enzyme are associated with Tay-Sachs disease. HexB is structurally similar to chitobiase, consisting of a beta sandwich structure; this structure is similar to that found in the cellulose-binding domain of cellulase from ''Cellulomonas fimi''.〔 This domain may function as a carbohydrate binding module.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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